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Qwen2.5 72B VRAM requirements

GPU memory for the weights and KV cache at FP16, FP8 and 4-bit, and how many GPUs that takes. Figures from the model's config.json.

Short answer

Qwen2.5 72B needs about 165 GB of GPU memory at FP16/BF16, 84 GB at FP8 and 47 GB at 4-bit to serve one user at an 8K-token context. Its 72.7B parameters take 145.4 GB at 16-bit, and that conversation adds 2.7 GB of KV cache. On NVIDIA H100 80 GB GPUs that is 4 GPUs (tensor parallel 4) at FP16 and 2 GPUs (tensor parallel 2) at FP8; for a desktop, at 4-bit it needs 2 RTX 5090s with a layer split, or one 96 GB Mac Studio.

Updated . KV cache at FP16, plus 10% headroom for activations and the runtime.

GPU memory by precision

WeightsWeight memory1 user, 8K context32 users, 8K context1 user, 32K context
FP16/BF16145.4 GB165 GB257 GB173 GB
FP872.7 GB84 GB176 GB93 GB
4-bit (INT4)40 GB47 GB140 GB56 GB

Required memory = (weights + KV cache) ÷ 0.9. An FP8 KV cache halves the cache share; set it in the calculator.

How many GPUs for one user at 8K context

GPUMemoryFP16/BF16FP84-bit (INT4)
Data center · tensor parallel
NVIDIA L40S48 GB4 GPUs · TP42 GPUs · TP21 GPU
NVIDIA RTX PRO 6000 Blackwell Server Edition96 GB2 GPUs · TP21 GPU1 GPU
NVIDIA H100 SXM80 GB4 GPUs · TP42 GPUs · TP21 GPU
NVIDIA H100 NVL94 GB2 GPUs · TP21 GPU1 GPU
NVIDIA H200141 GB2 GPUs · TP21 GPU1 GPU
NVIDIA B200180 GB1 GPU1 GPU1 GPU
NVIDIA B300288 GB1 GPU1 GPU1 GPU
AMD Instinct MI300X192 GB1 GPU1 GPU1 GPU
AMD Instinct MI355X288 GB1 GPU1 GPU1 GPU
Workstation & consumer · layer split
NVIDIA RTX PRO 6000 Blackwell Workstation Edition96 GB2 cards1 card1 card
NVIDIA GeForce RTX 309024 GB7 cards4 cards2 cards
NVIDIA GeForce RTX 409024 GB7 cards4 cards2 cards
NVIDIA GeForce RTX 509032 GB6 cards3 cards2 cards
Apple Mac Studio M3 Ultra / M5 Ultra96 GB (72 usable)3 Macs2 Macs1 Mac
Apple Mac Studio M3 Ultra / M5 Ultra256 GB (192 usable)1 Mac1 Mac1 Mac
Apple Mac Studio M5 Ultra512 GB (384 usable)1 Mac1 Mac1 Mac

Data center GPUs are counted at a tensor-parallel size (TP) that divides the model’s attention heads, within one 8-GPU server. Workstation and consumer cards are counted for a layer split, which works with any number of cards. Mac Studio counts about 75% of unified memory as usable by the GPU. Capacity only: speed depends on memory bandwidth and the serving stack.

Memory is step one. Throughput, latency, power and the network decide the real build.

Size my actual workload

Qwen2.5 72B architecture

Parameters
72.7B
Layers with a KV cache
80
Attention heads / KV heads
64 / 8
Head dimension
128
Attention
Grouped-query attention (8 query heads per KV head)
Maximum context
32,768 tokens
KV cache per token (FP16)
2 × 80 layers × 8 KV heads × 128 head dim × 2 bytes = 327,680 bytes (0.33 MB) per token

Source: Qwen/Qwen2.5-72B-Instruct config.json on Hugging Face. Parameter counts are the Hub’s count of the repo’s safetensors files, or the model card’s figure.

Questions about Qwen2.5 72B

How much VRAM does Qwen2.5 72B need?

About 165 GB at FP16/BF16, 84 GB at FP8 and 47 GB at 4-bit, for one user at an 8K-token context. That is 145.4 GB, 72.7 GB or 40 GB of weights, plus 2.7 GB of KV cache, plus 10% headroom for activations and the runtime. Serving 32 users at 8K each takes 257 GB at FP16 or 176 GB at FP8, because every conversation keeps its own KV cache.

How many H100 GPUs does Qwen2.5 72B need?

At FP16/BF16 it takes 4 GPUs (tensor parallel 4), for one user at 8K or for 32 users. At FP8, 2 GPUs (tensor parallel 2) for one user at 8K and 4 GPUs (tensor parallel 4) for 32 users. One user at FP8 takes 1 GPU on H200 (141 GB) and 1 GPU on B200 (180 GB).

Can Qwen2.5 72B run on an RTX 4090 or RTX 5090?

At 4-bit it needs about 47 GB for one user at 8K: 2 RTX 4090s or 2 RTX 5090s. At FP8 (84 GB) it takes 4 RTX 4090s or 3 RTX 5090s. Several cards work with a layer split, as in llama.cpp, which divides the model's layers between them.

Can Qwen2.5 72B run on a Mac Studio?

macOS lets the GPU use about 75% of unified memory by default: about 72 GB of a 96 GB, 192 GB of a 256 GB and 384 GB of a 512 GB Mac Studio. At 4-bit Qwen2.5 72B needs 47 GB for one user at 8K, so it fits one 96 GB Mac Studio; at FP8 (84 GB) it fits one 256 GB Mac Studio.

How large is Qwen2.5 72B's KV cache?

At FP16, 2 × 80 layers × 8 KV heads × 128 head dim × 2 bytes = 327,680 bytes (0.33 MB) per token. It uses grouped-query attention: 8 query heads share each KV head, which makes the cache 8× smaller than full multi-head attention. An 8K-token conversation holds 2.7 GB at FP16, and a 32K-token one holds 11 GB.

What is Qwen2.5 72B's maximum context length?

32,768 tokens, according to its Hugging Face configuration. One user at that full length holds 11 GB of KV cache at FP16, for 93 GB in total with FP8 weights, or 87 GB with an FP8 KV cache as well.

Other models

Not listed? The LLM GPU calculator sizes any Hugging Face model from its ID, link or config.json.

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